The 1080 kilometer route linking Lhasa with the Kathmandu remains the most popular overland route in Tibet. The Friendship Highway follows the western portion of Chinese National Highway 318 for 965 kilometers via Yamdrok Lake, Gyantse, Shigatse, and Everest Base Camp before descending down to the Tibet-Nepal border. At the Nepal border, the Friendship Highway continues on the Araniko Highway for a further 115 kilometers to the Nepal capital of Kathmandu. Starting in Lhasa, this route goes through many of the most popular tourist spots that the Tibet Autonomous Region (TAR) has to offer.
Here is a recommended itinerary for the route connecting Lhasa with Kathmandu, though this route can be modified in any way: